Tim Schafer clearly isn't a man who likes to rest on his laurels - we'd like to see sequels to pretty much every game he has ever made, but he doesn't seem to be interested in franchises. Undoubtedly, the Schafer game we'd most like to see followed up is 1998's Grim Fandango - quite simply the finest point-and-click adventure ever (although Schafer's own Full Throttle ran it close).
Grim Fandango, as much as it's possible to describe it, mashes up Mexico's Day of the Dead and Humphrey Bogart's entire oeuvre of films. It looks amazing, has a deliciously wacky and convoluted plot and is hilariously funny. Point-and-clicks have enjoyed something of a comeback recently, thanks to mobile phone games and Steam's rising popularity - so how about it, Tim?