The game will launch simultaneously on Vita and PS3 this autumn and offer cross-platform play, so you'll be able to save from either machine and then pick up where you left off whether at home or on the go.
Sanzaru president Glen Egan also told the PS Blog that Carmelita Fox will be a playable character.
"The game picks up where Sly 3 left off, and Sly is feigning amnesia so he can be with the love of his life, Carmelita," he said. "But when he rejoins the Cooper Gang on their time-traveling escapade to restore his family's legacy, you can be sure Carmelita will quickly become embroiled in their wild adventure.
"The portable version will contain all the same awesome Sly Cooper action you will find on the PS3 along with cool Vita-specific features that incorporate the front and rear touchscreens and motion controls."